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KMID : 0880520170530010028
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Chonnam Medical Journal
2017 Volume.53 No. 1 p.28 ~ p.36
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Versatile Functions of Caveolin-1 in Aging-related Diseases
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Nguyen Kim Cuc Thi
Cho Kyung-A
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Abstract
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Caveolin-1 (Cav-1) is a trans-membrane protein that is a major component of the caveolae structure on the plasma membrane. Cav-1 is involved in the regulation of various cellular processes, including cell growth, differentiation, endocytosis, and in particular it has been implied in cellular senescence. Here we review current knowledge about Cav-1 in cellular signaling and discuss the role of Cav-1 in aging-related diseases.
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KEYWORD
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Caveolin 1, Caveolae, Cell Aging, Endocytosis
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